Syphilis in the Eye: Recognizing Acute Syphilitic Posterior Placoid Chorioretinitis

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Atypical Acute Syphilitic Posterior Placoid Chorioretinitis

A 48-year-old man presented with visual dimness in the right eye that had developed 2 weeks previously. Dilated fundus examination showed few vitreous cells and numerous yellow, placoid lesions in both eyes. His right eye had more severe serous retinal detachment involving the macula. Fluorescein angiography demonstrated early irregular hypofluorescence with late staining in the areas of the ye...

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Severe acute syphilitic posterior placoid chorioretinitis with complete spontaneous resolution: The natural course

PURPOSE We report on a case of unilateral acute syphilitic posterior placoid chorioretinitis (ASPPC) with spontaneous resolution of the lesions, and discuss the role of an altered versus adequate immune response as the major pathogenic factor. METHODS We describe a case of acute loss of visual acuity (VA) in the left eye (LE) in a 55-year-old healthy man. RESULTS The patient presented with ...

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Posterior placoid chorioretinitis: An unusual ocular manifestation of syphilis

There appears to be a re-emergence of syphilis in recent times despite a steady decline in incidence for the past decade. Diagnosis of syphilis can be clinically challenging and ocular manifestations of syphilis have a myriad of presentations and severity. Ocular syphilis can occur at any stage of the disease and may also be the only presenting sign of syphilis. We report a case of acute unilat...

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Spectral domain optical coherence tomography findings in acute syphilitic posterior placoid chorioretinitis

BACKGROUND We describe the spectral domain optical coherence tomography (SD-OCT) findings in three patients with acute syphilitic posterior placoid chorioretinitis (ASPPC). The SD-OCT images demonstrate the pathologic changes in ASPPC with a high level of anatomic detail and may provide information about the pathophysiology of the disease. FINDINGS We report a series of three consecutive pati...

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Spectral-Domain Optical Coherence Tomography Features of Acute Syphilitic Posterior Placoid Chorioretinitis: The Role of Autoimmune Response in Pathogenesis

PURPOSE Syphilis is an infectious disease that can cause a wide variety of ocular signs. One of the rarest manifestations of ocular syphilis is acute syphilitic posterior placoid chorioretinitis (ASPPC). We report on the spectral-domain optical coherence tomography (SD-OCT) features of a case diagnosed with unilateral ASPPC. METHODS A 64-year-old man presented with a sudden loss of visual acu...

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ژورنال

عنوان ژورنال: American Medical Student Research Journal

سال: 2015

ISSN: 2333-4096

DOI: 10.15422/amsrj.2015.03.003